Mesquite occupies the northeast corner of Clark County and extends north into the southeast corner of Lincoln County. The eastern border of the city is the Arizona state line. The city is in the Virgin River valley, occupying the northern side of the river. The city lies adjacent to the Virgin Mountains in the northeastern Mojave Desert near the southern mouth of the Virgin River Gorge.

Mesquite was settled by Mormon pioneers in 1880, who called it Mesquite Flat. The community was finally established on the third attempt after having been flooded out from the waters of the Virgin River. The name was later shortened to Mesquite, and the city was incorporated 1984. The community was named for the mesquite timber near the original town site. Mesquite, like nearby Bunkerville, had its origins in farming. The Peppermill Mesquite casino, which opened in the 1970s, drove Mesquite's diversified economy. The city incorporated in 1984 and established a master development plan during the early 1990s. In the mid-1990s, more casinos opened. By 2006, Mesquite was one of the fastest-growing small towns in the United States, though the late-2000s recession led to the closure of both the Mesquite Star and Oasis (formerly The Peppermill) casinos.

When someday comes you'll need to get in.

When someday comes you'll need to be able to get around.