There are a number of highways including E75 and the main railway from Athens to Thessaloniki (Salonika) crossing through Thessaly. The region is directly linked to the rest of Europe through the International Airport of Central Greece located in Nea Anchialos a short distance from Larissa (about 60 km). Larissa lies on the river Pineios.
Larissa is a major agricultural center of Greece, due to the plain of Thessaly.
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